COMT, ген, чьи ОНП решают, быть ли вам сосредоточенным и бодрым или вальяжным и спокойным

COMT и его ОНП оказывают сильное воздействие на настроение, концентрацию внимания и выработку организмом эстрогена. От количества этого гормона зависят женский менструальный цикл, образование фиброзных опухолей и развитие некоторых видов рака.

Положительное влияние: сосредоточенность, энергичность, внимательность, хорошее расположение духа, здоровая кожа.

Негативное влияние: раздражительность, бессонница, тревожные расстройства, фиброзные опухоли, мигрень, ПМС, нетерпеливость, склонность к вредным привычкам.

1. Catechols found in quercetin: “COMT Gene,” Genetic Home Reference, 11 April, 2017, https://ghr.nlm.nih.gov/gene/COMT#resources.

2. Dopamine quinone is associated with Parkinson’s disease and ADHD medications: Miyazak, Ikuko, Asanuma, Masato. “Approaches to Prevent Dopamine Quinone-Induced Neurotoxicity,” Neurochemical Research, 04 September 2008, http://link.springer.com/article/10.1007/s11064-008-9843-1.

3. Toxicity of Methylphenidate: Sadasivan, Shankar et al. “Methylphenidate Exposure Induces Dopamine Neuron Loss and Activation of Microglia in the Basal Ganglia of Mice,” PLOS One, 21 March 2012, http://journals.plos.org/plosone/article?id=79461.1371/journal.pone.0033693.

4. Toxicity of Methylphenidate: Espay, AJ. et al. “Methylphenidate for gait impairment in Parkinson disease,” American Academy of Neurology, 5 April 2011, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3068005/.

5. Adderall can generate dopamine-quinone: German, Christopher L., Hanson, Glen R., Fleckenstein, Annette E., “Amphetamine and Methamphetamine Reduce Striatal Dopamine Transporter Function Without Concurrent Dopamine Transporter Relocalization,” Journal of Neurochemistry, 23 August 2012, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3962019/.

6. Two common reasons for magnesium deficiency: Janett, S. et al. “Hypomagnesemia Induced by Long-Term Treatment with Proton-Pump Inhibitors,” Gastroentology Research & Practice, 4 May 2015, https://www.ncbi.nlm.nih.gov/pubmed/26064102.

7. Two common reasons for magnesium deficiency: Kynast-Gales, SA, Massey, LK. “Effect of caffeine on circadian excretion of urinary calcium and magnesium,” Journal of American College of Nutrition, October 1994, https://www.ncbi.nlm.nih.gov/pubmed/7836625.

8. Damage from dioxins: Liu, J. et al. “Variants in maternal COMT and MTHFR genes and risk of neural tube defects in offspring,” Metabolic Brain Disease, 4 July 2014, https://www.ncbi.nlm.nih.gov/pubmed/24990354.

9. Hugs raise dopamine: “The Power of Love Hugs and Cuddles Have Long-Term Effects,” NIH News In Health, February 2007, https://newsinhealth.nih.gov/2007/february/docs/01features_01.htm.

Based on Ben Lynch. Dirty genes. 2018 by Dr. Ben Lynch LLC. HarperCollins Publishers