Ген GST/GPX: вызывает трудности с детоксикацией организма.

GST/GPX влияет на способность организма избавляться от токсинов.

Положительное влияние: вы сами можете вовремя понять, какие химикаты не переносите. Благодаря этому вредные вещества не успеют нанести серьезный ущерб вашему здоровью. Также в случае развития ряда заболеваний химиотерапия принесет вам бóльший лечебный эффект, чем другим людям.

Негативное влияние: гиперчувствительность к потенциально вредным химикатам. Развитие разного рода реакций, начиная от едва заметных симптомов, заканчивая серьезными аутоиммунными заболеваниями и раком. Также возможно повреждение ДНК — это увеличивает риск возникновения рака.

1. Dirty GST related to increased inflammation: Luo, L. et al. “Recombinant protein glutathione S-transferases P1 attenuates inflammation in mice,” Molecular Immunology, 28 October 2008, https://www.ncbi.nlm.nih.gov/pubmed?cmd=search&term=18962899&dopt=b.

2. Dirty GST related to overweight/obesity: National Center for Biotechnology Information, U.S. National Library of Medicine, Accessed April 2017, https://www.ncbi.nlm.nih.gov/pubmed/27657993,27281183,27271262,27179909,27113843,26429914,26329912,26295823,26295386,26252359,26044055,25880856,25606397,25532576,25010864,24840051,24839830,24716937,24664677,24205873?report=docsum.

3. Excess hydrogen peroxide relating to grey hair: Wood, JM et al. “Senile hair graying: H2O2-mediated oxidative stress affects human hair color by blunting methionine sulfoxide repair,” FASEB Journal, 23 February 2009, https://www.ncbi.nlm.nih.gov/pubmed/19237503.

4. Types of GST gene: “GST,” Gene Cards, Accessed April 2017, http://www.genecards.org/Search/Keyword?queryString=%22GST%22.

5. Microbiome combats chemical and oxidative stresses: Ziglari, Tahereh, Allameh, Abdolamir. “The Significance of Glutathione Conjugation in Aflatoxin Metabolism,” Aflatoxins — Recent Advances and Future Prospects, 23 January 2013, https://www.intechopen.com/books/aflatoxins-recent-advances-and-future-prospects/the-significance-of-glutathione-conjugation-in-aflatoxin-metabolism.

6. Ease in achieving optimal weight: National Center for Biotechnology Information, U.S. National Library of Medicine, Accessed April 2017, https://www.ncbi.nlm.nih.gov/pubmed/27657993,27281183,27271262,27179909,27113843,26429914,26329912,26295823,26295386,26252359,26044055,25880856,25606397,25532576,25010864,24840051,24839830,24716937,24664677,24205873?report=docsum.

7. Ease in achieving optimal weight: Crinnion, Walter. “Clean, Green, and Lean: Get Rid of the Toxins That Make You Fat,” Amazon, Accessed April 2017, https://www.amazon.com/Clean-Green-Lean-Toxins-That-ebook/dp/B00DNKYI8E/ref=tmm_kin_swatch_0?_encoding=UTF8&qid=&sr=.

8. Effects of low glutathione: Kut, JL. et al. “Regulation of murine T-lymphocyte function by spleen cell-derived and exogenous serotonin,” Immunopharmacology & Immunotoxicology, 1992, https://www.ncbi.nlm.nih.gov/pubmed/1294623.

9. Th1/Th2 balance: the hypothesis, its limitations, and implications for health and disease: Kidd P., Altern. Med. Rev., August, 2003, https://www.nebi.nlm.nih.gov/pubmed/12946237

10. Damaged glutathione can further damage cells: Mulherin DM, Thurnham DI, Situnayake RD. “Glutathione reductase activity, riboflavin status, and disease activity in rheumatoid arthritis,” Annals of The Rheumatic Diseases, November 1996, https://www.ncbi.nlm.nih.gov/pubmed/8976642.

11. Damaged glutathione can further damage cells: Taniguchi, M, Hara, T. “Effects of riboflavin and selenium deficiencies on glutathione and its relating enzyme activities with respect to lipid peroxide content of rat livers,” Journal of Nutritional Science and Vitaminology, June 1983, https://www.ncbi.nlm.nih.gov/pubmed/6619991.

12. Selenium in brazil nuts: “Selenium,” National Institutes of Health, Accessed April 2017, https://ods.od.nih.gov/factsheets/Selenium-HealthProfessional/.

13. Lungs need adequate hydrogen sulfide to breathe: Wang, P. et al. “Hydrogen sulfide and asthma,” Experimental Physiology, 10 June 2011, https://www.ncbi.nlm.nih.gov/pubmed/21666034

14. Fiber binds to xenobiotics: Stein, K. et al. “Fermented wheat aleurone induces enzymes involved in detoxification of carcinogens and in antioxidative defence in human colon cells,” The British Journal of Nutrition, 28 June 2010, https://www.ncbi.nlm.nih.gov/pubmed/20579402.

15. Healthy ways to sweat: Genuis, SJ, et al. “Blood, urine, and sweat (BUS) study: monitoring and elimination of bioaccumulated toxic elements,” Archives of Environmental Contamination and Toxicology, 6 November 2010, https://www.ncbi.nlm.nih.gov/pubmed/21057782.

Based on Ben Lynch. Dirty genes. 2018 by Dr. Ben Lynch LLC. HarperCollins Publishers